Hydrochloric Acid → Hydrochloric Acid

HRID 185351Notes

Reaction equation

HRID 185351 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][C:11]([CH2:14][NH:15][c:16]2[nH:17][c:18]3[c:19]([n:20]2)[cH:21][cH:22][c:23]([C:25](=[O:26])[O:27][CH3:28])[cH:24]3)([F:29])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:37][OH:38].[ClH:36].[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1>>[ClH:36].[NH:8]1[CH2:9][CH2:10][C:11]([CH2:14][NH:15][c:16]2[nH:17][c:18]3[c:19]([n:20]2)[cH:21][cH:22][c:23]([C:25](=[O:26])[O:27][CH3:28])[cH:24]3)([F:29])[CH2:12][CH2:13]1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 690670954-Fluoro-4-({[5-(methoxycarbonyl)benzimidazol-2-yl]amino}methyl)piperidinecarboxylic acid tert-butyl ester

Product 2

HCID 313Hydrochloric AcidHCID 69066458methyl 2-[(4-fluoropiperidin-4-yl)methylamino]-3H-benzimidazole-5-carboxylate

Sources & evidence

ORD record
ord-b83ea73de4504c3285b69b9d13680d8c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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