HRID1853726

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31398

N-Chlorosuccinimide

C4H4ClNO2

结构：COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc([C@H](C)CNC(=O)OC(C)(C)C)cc1

HCID67449775

未命名化合物

PRODUCTS

生成物

结构：COc1cc(Cl)c2[nH]c(=O)c3sccc3c2c1-c1ccc([C@H](C)CNC(=O)OC(C)(C)C)cc1

HCID67450209

未命名化合物

收率 58%

PROCEDURE

实验过程

Following General Procedure H, (S)-tert-butyl 2-(4-(8-methoxy-4-oxo-4,5-dihydrothieno[2,3-c]quinolin-9-yl)phenyl)propylcarbamate (500 mg, 1.08 mmol) was reacted with NCS (175 mg, 1.29 mmol)) to afford the desired product (310 mg, 58%) as a yellow solid: ESI MS m/z 499 [C26H27ClN2O4S+H]+.