Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2(1H)-Pyrazinone, sodium salt (1:1) | HCID 23668973 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 23086769 | HCID 23086769 | — |
Reaction Steps
A mixture of 632 mg Sodium pyrazin-2-olate and 720 mg 1-Fluoro-4-nitro-benzene and 3.3 g Cs2CO3 in 13 mL DMF was heated to 35° C. for 6 h. This solution was poured on to 300 mL of water and the resulting precipitate was collected by filtration to yield a bright yellow crystalline product, which was dried under reduced pressure. Yield: 545 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07741341B2 |
|---|
| Source dataset | uspto-grants-2010_06 |
|---|
| ORD ID | ord-dd3cb375507c46c8b46d939f3caf9af4 |
|---|
| Source note | uspto-grants-2010_06 |
|---|
