反应详情

To a solution of 520 mg 1-(4-Nitro-phenyl)-1H-pyrazin-2-one in 26 mL ethyl acetate and 1.3 mL ethanol, 2.7 g SnCl2 dihydrate were added and the reaction mixture was heated to reflux for 6 h. Then, after cooling to RT the mixture was stirred for 16 h. The precipitated product was collected by filtration and was pure enough for the next reaction step. Yield: 450 mg.

1. temperaturethe reaction mixture was heated
2. temperatureto reflux for 6 h
3. filtrationThe precipitated product was collected by filtration
4. customwas pure enough for the next reaction step