HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → 5-(tert-Butyl)-3-((tert-butylamino)methyl)-2'-chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | 5-(tert-Butyl)-2'-chloro-2-hydroxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-carbaldehyde | HCID 86718727 | — |
| Product | 5-(tert-Butyl)-3-((tert-butylamino)methyl)-2'-chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol hydrochloride | HCID 86718728 | — |
Reaction Steps
5-(tert-Butyl)-3-((tert-butylamino)methyl)-2′-chloro-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-ol hydrochloride was prepared as a white solid using the procedure described in Example 9 from 5-(tert-butyl)-2′-chloro-2-hydroxy-4′-(trifluoromethyl)-[1,1′-biphenyl]-3-carbaldehyde and tert-butylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962657B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-ec404715a197499485943955f98d44de |
| Source note | uspto-grants-2015_02 |