Tert-Butylamine → HCID 86718744, compound

HRID 1854196Notes

Reaction equation

[CH2:1]([C:5]1[CH:6]=[C:7]([CH:20]=O)[C:8]([OH:19])=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[C:13]([Cl:18])[CH:12]=2)[CH:10]=1)[CH2:2][CH2:3][CH3:4].[C:22]([NH2:26])([CH3:25])([CH3:24])[CH3:23]>>[ClH:17].[CH2:1]([C:5]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[C:13]([Cl:18])[CH:12]=2)[C:8]([OH:19])=[C:7]([CH2:20][NH:26][C:22]([CH3:25])([CH3:24])[CH3:23])[CH:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 86718746HCID 86718746, compound

Product 1

HCID 86718744HCID 86718744, compound

Procedure

5-Butyl-3-((tert-butylamino)methyl)-3′,4′-dichloro-[1,1′-biphenyl]-2-ol hydrochloride was prepared as a white solid using the procedure described in Example 9 from 5-butyl-3′,4′-dichloro-2-hydroxy-[1,1′-biphenyl]-3-carbaldehyde and tert-butylamine.

Sources & evidence

ORD record: ord-ce96bffae8c7484caab15184e559e45c
Source dataset: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08962657B2

Reaction notes

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