Tert-Butylamine → HCID 86718756, compound

HRID 1854200Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=3)[CH:12]=[C:11]([CH:26]=O)[C:10]=2[OH:28])[CH:5]=[CH:6][C:7]=1[Cl:8].[C:29]([NH2:33])([CH3:32])([CH3:31])[CH3:30]>>[ClH:1].[C:29]([NH:33][CH2:26][C:11]1[CH:12]=[C:13]([CH2:15][CH2:16][CH2:17][CH2:18][C:19]2[CH:20]=[CH:21][C:22]([Cl:25])=[CH:23][CH:24]=2)[CH:14]=[C:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)[C:10]=1[OH:28])([CH3:32])([CH3:31])[CH3:30]

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 86718758HCID 86718758, compound

Product 1

HCID 86718756HCID 86718756, compound

Procedure

3-((tert-Butylamino)methyl)-3′,4′-dichloro-5-(4-(4-chlorophenyl)butyl)-[1,1′-biphenyl]-2-ol hydrochloride was prepared as a white solid using the procedure described in Example 9 from 3′,4′-dichloro-5-(4-(4-chlorophenyl)butyl)-2-hydroxy-[1,1′-biphenyl]-3-carbaldehyde and tert-butylamine.

Sources & evidence

ORD record: ord-6a8e0b3b0eb84dd4818d81c0c6511b39
Source dataset: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08962657B2

Reaction notes

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