HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,6-dimethoxy-1,3,5-triazine → 3-(4,6-dimethoxy-1,3,5-triazin-2-yl)-5,7-difluoro-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,6-dimethoxy-1,3,5-triazine | HCID 18450 | — |
| Reactant | 5,7-difluoro-1,3-dihydro-2H-indol-2-one | HCID 2778963 | — |
| Product | 3-(4,6-dimethoxy-1,3,5-triazin-2-yl)-5,7-difluoro-1,3-dihydro-2H-indol-2-one | HCID 67983015 | — |
Reaction Steps
5,7-Difluoro-1,3-dihydro-2H-indol-2-one (1.69 g) and 2-chloro-4,6-dimethoxy-1,3,5-triazine (2.13 g) are reacted analogously to Example 1 Variant A. This gives the title compound as solid in an HPLC purity of 93% area (2.82 g, 85% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962828B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c4a011ec440c452fb85dd099dc73a91f |
| Source note | uspto-grants-2015_02 |