2-Chloro-4,6-dimethoxy-1,3,5-triazine → HCID 57345409, compound

HRID 1854772Notes

Reaction equation

HRID 1854772 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[CH2:7]2.Cl[C:13]1[N:18]=[C:17]([O:19][CH3:20])[N:16]=[C:15]([O:21][CH3:22])[N:14]=1>>[CH3:22][O:21][C:15]1[N:16]=[C:17]([O:19][CH3:20])[N:18]=[C:13]([CH:7]2[C:6]3[C:10](=[C:2]([Cl:1])[CH:3]=[CH:4][CH:5]=3)[NH:9][C:8]2=[O:11])[N:14]=1

Participants

3

Reactant 2

HCID 184502-Chloro-4,6-dimethoxy-1,3,5-triazineHCID 37310107-Chloro-1,3-dihydro-2H-indol-2-one

Product 1

HCID 57345409HCID 57345409, compound

Procedure

7-Chloro-1,3-dihydro-2H-indol-2-one (101.5 g) and 2-chloro-4,6-dimethoxy-1,3,5-triazine (152 g) are reacted analogously to Example 1 Variant A. This gives the title compound as solid in an HPLC purity of 99% area (181.9 g, 97% of theory).

Sources & evidence

ORD record
ord-72ed9b1e450d42ea8e100ad9dff8a3cc
Source dataset
uspto-grants-2015_02
Patent number
US08962828B2

Reaction notes

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