4-Chlorophenol → HCID 44192598, compound

HRID 1855340Notes

Reaction equation

HRID 1855340 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Cl[C:10]1[CH:15]=[C:14]([CH3:16])[N:13]=[C:12]([NH:17][C:18]2[CH:23]=[CH:22][C:21]([N:24]3[CH:28]=[C:27]([CH3:29])[N:26]=[CH:25]3)=[C:20]([O:30][CH3:31])[CH:19]=2)[N:11]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:10]2[CH:15]=[C:14]([CH3:16])[N:13]=[C:12]([NH:17][C:18]3[CH:23]=[CH:22][C:21]([N:24]4[CH:28]=[C:27]([CH3:29])[N:26]=[CH:25]4)=[C:20]([O:30][CH3:31])[CH:19]=3)[N:11]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 46844-ChlorophenolHCID 57829826HCID 57829826, compound

Product 1

HCID 44192598HCID 44192598, compoundYield 73%

Procedure

The title compound was prepared in analogous manners as described in example 9) from 4-chlorophenol and (4-chloro-6-methyl-pyrimidin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine. It was obtained in 73% yield as a pale-brown solid.

Workup

  1. customIt was obtained in 73% yield as a pale-brown solid

Sources & evidence

ORD record
ord-c0201103ea2d46fd9c33b5b16f2ffe55
Source dataset
uspto-grants-2015_02
Patent number
US08962834B2

Reaction notes

Loading…