HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate → HCID 57829726, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate | HCID 3696469 | — |
| Reactant | 3-methoxy-4-(4-methyl-1H-imidazol-1-yl)aniline | HCID 45480181 | — |
| Product | HCID 57829726 | HCID 57829726 | — |
Reaction Steps
The title compound was prepared in analogous manner as described in example 1e) from 3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamine and methyl 2-chloro-4-trifluoromethyl-pyrimidine-5-carboxylate. The reaction was heated to reflux for 16 h. The title compound was obtained as a pale-yellow solid in 20% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962834B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-094217d71e0f49a7b7da80930b1c0310 |
| Source note | uspto-grants-2015_02 |