HCID 54104092, compound → Ethyl 4-(4-chloro-phenyl)-2-[3-fluoro-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-5-carboxylate

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Reaction Steps

The title compound was prepared from crude ethyl 3-dimethylamino-2-(4-chloro-benzoyl)-acrylate (89 mg, 0.3 mmol) and N-[3-fluoro-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (80 mg, 0.22 mmol) using in analogous manner the procedure described in example 28b). Obtained as a pale-yellow solid (28 mg, 28%). Mp 232-234° C.

Provenance & Evidence