HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyl-2-chloro-pyrimidine → (4-Benzyl-pyrimidin-2-yl)-[3-fluoro-4-(4-methyl-imidazol-1-yl)-phenyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyl-2-chloro-pyrimidine | HCID 18353331 | — |
| Reactant | 3-Fluoro-4-(4-methyl-1H-imidazol-1-yl)aniline | HCID 21876638 | — |
| Product | (4-Benzyl-pyrimidin-2-yl)-[3-fluoro-4-(4-methyl-imidazol-1-yl)-phenyl]-amine | HCID 57829814 | — |
Reaction Steps
The title compound was prepared from 3-fluoro-4-(4-methyl-imidazol-1-yl)-phenylamine (94 mg, 0.49 mmol) and 4-benzyl-2-chloro-pyrimidine (100 mg, 0.49 mmol) in analogous manner to the procedure described in example 1e). Obtained as a pale-yellow solid (50 mg, 29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962834B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-115b1237ad7d46588d56d91047ebfddf |
| Source note | uspto-grants-2015_02 |