HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-fluoro-4-(1H-1,2,4-triazol-1-yl)aniline → (4-Benzyl-6-methyl-pyrimidin-2-yl)-(3-fluoro-4-[1,2,4]triazol-1-yl-phenyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-fluoro-4-(1H-1,2,4-triazol-1-yl)aniline | HCID 22329546 | — |
| Reactant | 4-Benzyl-2-chloro-6-methyl-pyrimidine | HCID 86633618 | — |
| Product | (4-Benzyl-6-methyl-pyrimidin-2-yl)-(3-fluoro-4-[1,2,4]triazol-1-yl-phenyl)-amine | HCID 57829862 | — |
Reaction Steps
The title compound was prepared from 3-fluoro-4-[1,2,4]triazol-1-yl-phenylamine (81.4 mg, 0.46 mmol) and 4-benzyl-2-chloro-6-methyl-pyrimidine (100 mg, 0.46 mmol) in analogous manner to the procedure described in example 1e). Obtained as a light yellow wax (98 mg, 60%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962834B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c80720a1e17040bd9d1e12090bf804b2 |
| Source note | uspto-grants-2015_02 |