2,4-Dichloro-6-methylpyrimidine → HCID 86633627, compound

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Reaction Steps

Prepared in analogy to example 98a), using 2,4-dichloro-6-methylpyrimidine and 1-methanesulfonyl-piperazine. The title compound was isolated as a yellow solid in a yield of 41%. MS ISP (m/e): 291.1 (100) [(M+H)+]. 1H NMR (DMSO-D6, 300 MHz): δ (ppm)=6.81 (s, 1H), 3.80-3.70 (m, 4H), 3.20-3.15 (m, 4H), 2.90 (s, 3H), 2.26 (s, 3H).

Provenance & Evidence