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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1855512Generated: November 2, 2026

4-(Pyridin-4-yl)aniline → HCID 57829745, compound

https://huagongshe.com/reaction/1855512

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Pyridin-4-yl)anilineHCID 1512654—
Reactant4-Benzyl-2-chloro-6-methyl-pyrimidineHCID 86633618—
ProductHCID 57829745HCID 57829745—

Reaction Steps

Prepared in analogy to example 62 from 4-(pyridin-4-yl) aniline and 4-benzyl-2-chloro-6-methyl-pyrimidine (example 43a). The title compound was obtained as a brownish oil (Yield=31%). MS ISP (m/e): 353.1 (100) [(M+H)+]. 1H NMR (DMSO-D6, 300 MHz): δ (ppm)=9.80 (s, 1H), 8.57 (d, 2H), 7.95 (d, 2H), 7.74 (d, 2H), 7.69 (d, 2H), 7.40-7.15 (m, 5H), 6.68 (s, 1H), 3.95 (s, 2H), 2.34 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08962834B2
Source datasetuspto-grants-2015_02
ORD IDord-1357daf20c7f4e77966b55961173d4d2
Source noteuspto-grants-2015_02