Benzaldehyde → 1-(1h-Benzo[d]imidazol-5-yl)-5-phenylimidazolidine-2,4-dione

HRID 1855540Notes

Reaction equation

HRID 1855540 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]2[N:6]=[CH:7][NH:8][C:4]=2[CH:3]=1.[CH:11](=[O:18])C1C=CC=CC=1.[CH2:19]([N+]#[C-])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[O:28]([C:30]#[N:31])[K]>>[NH:6]1[C:5]2[CH:9]=[CH:10][C:2]([N:1]3[CH:19]([C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=4)[C:30](=[O:28])[NH:31][C:11]3=[O:18])=[CH:3][C:4]=2[N:8]=[CH:7]1

Participants

5

Reactant 4

HCID 240BenzaldehydeHCID 136235-AminobenzimidazoleHCID 82558Benzyl isocyanideHCID 178418250HCID 178418250, compound

Product 1

HCID 1785185301-(1h-Benzo[d]imidazol-5-yl)-5-phenylimidazolidine-2,4-dione

Procedure

The compound was synthesized starting from 5-aminobenzimidazole 1.331 g (10 mmol), benzaldehyde 1.02 mL (10 mmol), benzyl isonitrile 1.22 mL (10 mmol) and KOCN 0.84 g (10 mmol) as described in method 1.

Workup

  1. customThe compound was synthesized

Sources & evidence

ORD record
ord-bdb507e3ac3942e8a5c52c4a668058e7
Source dataset
uspto-grants-2015_02
Patent number
US08962860B2

Reaction notes

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