Chlorine → 2-Chloro-4-(trifluoromethyl)phenol

Participants

Reaction Steps

Chlorine gas is passed through a flow meter into a solution of α,α,α-trifluoro-p-cresol (4.05 g. 0.025 mole) in ethylene dichloride (200 ml.) at 0° C. until the theoretical volume has been absorbed. The solvent is stripped off and the residue distilled to give 2-chloro-α,α,α-trifluoro-p-cresol (3.5 g. 71%) b.p. 80°-82° C. at 33 mm.

Provenance & Evidence