Potassium cyanate → Sulbenox

HRID 1855716Notes

Reaction equation

HRID 1855716 reaction equation
Cl.[O:2]=[C:3]1[C:8]2[S:9][CH:10]=[CH:11][C:7]=2[CH:6]([NH2:12])[CH2:5][CH2:4]1.[O-:13][C:14]#[N:15].[K+]>O>[O:2]=[C:3]1[C:8]2[S:9][CH:10]=[CH:11][C:7]=2[CH:6]([NH:12][C:14]([NH2:15])=[O:13])[CH2:5][CH2:4]1

Participants

4

Reactant 2

HCID 11378442Potassium cyanateHCID 233477954,5,6,7-Tetrahydro-7-oxobenzo[b]thiophen-4-amine hydrochloride

Product 1

HCID 65473Sulbenox

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

An aqueous solution of 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophen-4-amine hydrochloride (1.01 g/5 ml water) is treated with 0.81 g of potassium cyanate in 2 ml of water at pH 6-7 to afford the title compound, which is collected and washed with water to afford 0.93 g, m.p. 241° C. to 242° C. dec.

Sources & evidence

ORD record
ord-5cd6fc17efc6410fb75d3f7f28d37424
Source dataset
uspto-grants-1980_08
Patent number
US04216149

Reaction notes

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