HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 1-Methyl-3-(4,5,6,7-tetrahydro-7-oxobenzo[b]thien-4-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Cyanic acid, methyl ester | HCID 137201 | — |
| Reactant | 4-Amino-5,6-dihydro-1-benzothiophen-7(4H)-one | HCID 23347796 | — |
| Product | 1-Methyl-3-(4,5,6,7-tetrahydro-7-oxobenzo[b]thien-4-yl)urea | HCID 13037017 | — |
Reaction Steps
In 50 ml of dichloromethane, 8.1 g of 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophen-4-amine is stirred under a nitrogen atmosphere and 2.9 g of methyl cyanate in 50 ml of dichloromethane is added dropwise at below 30° C. After stirring for an hour, the title compound is collected, m.p. 212° C. to 215° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04216149 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-c8bafe927e2044fe92ddf4859c71a82a |
| Source note | uspto-grants-1980_08 |