HCID 12680125, compound → HCID 12482555, compound

Participants

Reaction Steps

A 7.2 g. portion of the above benzamide in 100 g. of polyphosphoric acid is heated at 115°-125° C. for 2 hours, cooled, poured into ice and water and extracted with chloroform. The extract is washed with water, dried over magnesium sulfate, filtered and evaporated, giving 4H-thieno[3,4-b][1,4]benzodiazepin-9(10H)-one as a yellow solid.

Provenance & Evidence