Hydrochloric Acid → HCID 23348503, compound

Participants

Reaction Steps

19.0 g (0.0524 mol) of this ester are dissolved in 250 ml of acetone and mixed with 52.4 ml of N sodium hydroxide solution. The mixture is stirred at room temperature for 18 hours, 52.4 ml of N hydrochloric acid are added, the mixture is evaporated and the residue is re-crystallised from methanol, to yield 3-{3-[3-(4-phenyl-1-piperazinyl)-propyl]-ureido}propionic acid. Yield: 15.9 g (90% of theory). Melting range: 169°-171° C. ##STR27##

Provenance & Evidence