Acetic Anhydride → HCID 12837908, compound

HRID 1855768Notes

Reaction equation

HRID 1855768 reaction equation
[ClH:1].[CH3:2][N:3]([CH3:8])[C:4](=[NH:7])[CH2:5][SH:6].[C:9](OC(=O)C)(=[O:11])[CH3:10]>C(O)(=O)C>[ClH:1].[CH3:2][N:3]([CH3:8])[C:4](=[NH:7])[CH2:5][S:6][C:9](=[O:11])[CH3:10]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20067108HCID 20067108, compound

Product 1

HCID 12837908HCID 12837908, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a solution of 1.54 g. of N,N-dimethyl-2-(mercapto)acetamidine hydrochloride in 15 ml. of acetic acid was added 2 ml. of acetic anhydride, and the reaction mixture was heated at 55°-60° C. for 3 hours, after which it was concentrated in vacuo. The product was crystallized from ether, filtered, and air dried, then recrystallized from ethanol to yield 1.1 g., m.p. 162°-5°-163° C.

Workup

  1. concentrationafter which it was concentrated in vacuo
  2. customThe product was crystallized from ether
  3. filtrationfiltered
  4. customair dried
  5. customrecrystallized from ethanol
  6. customto yield 1.1 g
  7. customm.p. 162°-5°-163° C.

Sources & evidence

ORD record
ord-276a38e3a6494806884b6dba8a3e6866
Source dataset
uspto-grants-1980_08
Patent number
US04216160

Reaction notes

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