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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1855866Generated: October 31, 2026

Methyl iodide → HCID 136045968, compound

https://huagongshe.com/reaction/1855866

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium ethoxideHCID 2723922—
ReactantHCID 23349180HCID 23349180—
SolventEthanolHCID 702—
ProductHCID 136045968HCID 136045968—

Reaction Steps

Treatment of 5-(3-pyridylmethyl)-6-methyl-2-thiouracil with methyl iodide and sodium ethoxide in ethanol at 0° followed by acidification gave 2-methylthio-5-(3-pyridylmethyl)-6-methyl-4-pyrimidone m.p. 208°-211°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04216318
Source datasetuspto-grants-1980_08
ORD IDord-76972377ce3645a6b157e5bb8f1f61a2
Source noteuspto-grants-1980_08