HCID 178444822, compound → HCID 178444821, compound

Participants

Reaction Steps

A mixture of the compound of Example III (17 g, 0.048 mole), ethanol (250 ml), and 5% Pd/C-50% H2O (1.0 g) was subjected to hydrogenation at room temperature for 4 hours, using 6.0 psia H2 (theory: 5.9 psia H2). The catalyst was removed by filtration, the filtrate was diluted with anhydrous ether (1000 ml), and cooled. The product was collected by filtration and air dried; m.p. 148°-150°, yield: 15 g (97%).

Provenance & Evidence