Potassium Cation → 2-Butyl-1-{1-[3-(4-fluorophenylsulfanyl)-propyl]-piperidin-4-yl}-1H-benzimidazole

HRID 185609Notes

Reaction equation

HRID 185609 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][S:5][c:6]1[cH:7][cH:8][c:9]([F:12])[cH:10][cH:11]1.[CH2:13]([CH2:14][CH2:15][CH3:16])[c:17]1[n:18][c:19]2[c:20]([n:21]1[CH:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1)[cH:28][cH:29][cH:30][cH:31]2.[K+:32].[K+:33].[O-:34][C:35]([O-:36])=[O:37].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[OH2:38]>>[CH2:2]([CH2:3][CH2:4][S:5][c:6]1[cH:7][cH:8][c:9]([F:12])[cH:10][cH:11]1)[N:25]1[CH2:24][CH2:23][CH:22]([n:21]2[c:17]([CH2:13][CH2:14][CH2:15][CH3:16])[n:18][c:19]3[c:20]2[cH:28][cH:29][cH:30][cH:31]3)[CH2:27][CH2:26]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 14575314Benzene, 1-[(3-bromopropyl)thio]-4-fluoro-HCID 685849422-butyl-1-piperidin-4-yl-1H-benzimidazole

Product 1

HCID 585995222-Butyl-1-{1-[3-(4-fluorophenylsulfanyl)-propyl]-piperidin-4-yl}-1H-benzimidazole

Sources & evidence

ORD record
ord-f00b73d9b76f46e19e0165dc5582ba26
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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