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HRID1856273

反应详情

EQUATION

反应方程式

HRID 1856273 的结构方程式

REACTANTS

反应物

2
反应SMILES：COc1c(N)ccnc1CO
HCID20474201

2-Pyridinemethanol, 4-amino-3-methoxy-

C7H10N2O2

反应SMILES：O=N[O-].[Na+]
HCID23668193

Sodium Nitrite

NNaO2

PRODUCTS

产物

1
反应SMILES：COc1c(O)ccnc1CO
HCID178493894

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：O=S(=O)(O)O
溶剂HCID1118

Sulfuric acid

H2O4S

PROCEDURE

实验过程

4-Amino-2-hydroxymethyl-3-methoxypyridine is diazotised in dilute sulphuric acid with sodium nitrite and the diazonium compound is warmed to give 4-hydroxy-2-hydroxymethyl-3-methoxypyridine which may be demethylated with hydrobromic acid.