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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1856273Generated: November 1, 2026

4-Amino-2-hydroxymethyl-3-methoxypyridine → HCID 178493894, compound

https://huagongshe.com/reaction/1856273

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-hydroxymethyl-3-methoxypyridineHCID 20474201—
ReactantSodium NitriteHCID 23668193—
SolventSulfuric AcidHCID 1118—
ProductHCID 178493894HCID 178493894—

Reaction Steps

4-Amino-2-hydroxymethyl-3-methoxypyridine is diazotised in dilute sulphuric acid with sodium nitrite and the diazonium compound is warmed to give 4-hydroxy-2-hydroxymethyl-3-methoxypyridine which may be demethylated with hydrobromic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04218452
Source datasetuspto-grants-1980_08
ORD IDord-c4e4477846ec4dd087c170c9e7edd37a
Source noteuspto-grants-1980_08