Maleic Anhydride → HCID 178456689, compound

Participants

Reaction Conditions

Reaction Steps

The following example illustrates the preparation of the novel compounds: ##STR6## 58.8 g (0.6 mol) of maleic anhydride were added to a solution of 73.8 g (0.6 mol) of isopropylhydrazine sulphate in 180 ml of water and 10 ml of concentrated hydrochloric acid at 60° C. The mixture was then boiled for 3 hours under reflux after which it was cooled to 0° C. After half an hour, the product which had precipitated was filtered off. 59 g (64% of theory) of 1-isopropyl-1,6-dihydro-3-hydroxy-6-oxo-pyridazine were thus obtained in the form of colorless crystals of melting point 148° C.

Provenance & Evidence