HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 23345040, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | HCID 23345027 | HCID 23345027 | — |
| Solvent | Chloroform methanol | HCID 21584188 | — |
| Product | HCID 23345040 | HCID 23345040 | 19.8% |
Reaction Steps
Analogously to Example 7, using 10 mmol of 4-[3-(3-bromobutoxy)-4-methoxyphenyl]-2-pyrrolidone and 11 mmol of 1-phenylpiperazine (95% strength), 4-{4-methoxy-3-[3-methyl-3-(4-phenylpiperazin-1-yl)propoxy]phenyl}-2-pyrrolidone is obtained in a 19.8% yield, m.p. 88°-90° (ethanol; after chromatography methanol/chloroform 1:9).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04219551 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-622da1d2afda40a180ac280008ad7ef7 |
| Source note | uspto-grants-1980_08 |