2-Amino-5-chloropyridine → HCID 23345083, compound

Participants

Reaction Steps

2,6-Dichlorobenzoyl isocyanate (2.2 grams; 0.01 mole) and 5-chloro-2-aminopyridine (1.3 grams; 0.01 mole) were mixed in about 50 ml. of ethyl acetate, at room temperature, and the reaction mixture was stirred overnight (about 18 hours) at room temperature. Solvent was then evaporated, water was added, and the product was extracted with ethyl acetate. The ethyl acetate was evaporated, and the product recrystallized from ethanol, m.p., 211°-215° C. Elemental analysis showed the following:

Provenance & Evidence