HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-(trifluoromethyl)pyridine → HCID 13023075, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-(trifluoromethyl)pyridine | HCID 735862 | — |
| Reactant | 2,6-Dichlorobenzoyl isocyanate | HCID 12912739 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 13023075 | HCID 13023075 | — |
Reaction Steps
2,6-Dichlorobenzoyl isocyanate (1.1 grams; 0.005 mole) and 5-(trifluoromethyl)-2-aminopyridine (800 mg; 0.005 mole) were mixed in 50 ml. of ethyl acetate at room temperature and stirred overnight (about 18 hours) at room temperature. Solvent was then evaporated and the product recrystallized from ethanol, m.p. 228°-230° C., yield 200 mg. Elemental analysis showed:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04219557 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-9a762a3229954e8399cac1931635a0ca |
| Source note | uspto-grants-1980_08 |