HCID 53911873, compound → HCID 54540261, compound

HRID 1856498Notes

Reaction equation

HRID 1856498 reaction equation
[N+:1]([CH2:4][CH2:5][CH2:6][CH2:7][O:8][C:9](=[O:25])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([O-])=O>CCO.C1COCC1.[Zn]>[NH2:1][CH2:4][CH2:5][CH2:6][CH2:7][O:8][C:9](=[O:25])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

4

Reactant 1

HCID 53911873HCID 53911873, compound

Product 1

HCID 54540261HCID 54540261, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 21873804Tetrahydrofuran ethanolSolvent

Procedure

Hexadecanoic acid (4-nitrobutyl)ester was reduced with zinc in EtOH/THF/6 nHCl for 30 minutes at 35°-35°. Work up in the cold via basification with ammonia and extraction with methylene chloride yielded a crude residue. Crystallization from ether furnished off-white crystals, m.p. 59°-61°.

Workup

  1. extractionwith ammonia and extraction with methylene chloride

Sources & evidence

ORD record
ord-650418e33a3c4bb88c6f6af3c4b56a85
Source dataset
uspto-grants-1980_08
Patent number
US04219660

Reaction notes

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