Hydrochloric Acid → HCID 20288042, 화합물

HRID 1856553노트

반응식

HRID 1856553 반응식
CC([N:4]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:6]([CH2:13][CH2:14][C:15](=[O:17])[CH3:16])[C:5]1=[O:18])=C.Cl>CC(O)C>[O:17]=[C:15]([CH3:16])[CH2:14][CH2:13][N:6]1[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH:4][C:5]1=[O:18]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 202880381,3-dihydro-1-(1-methylethenyl)-3-(3-oxobutyl)-2H-benzimidazol-2-one

생성물 1

HCID 20288042HCID 20288042, 화합물수율 73.4%

시약·촉매·용매 1

HCID 3776Isopropanol용매2회

실험 절차

A mixture of 48.8 parts of 1,3-dihydro-1-(1-methylethenyl)-3-(3-oxobutyl)-2H-benzimidazol-2-one, 12 parts of 2-propanol, saturated with gaseous hydrogen chloride and 240 parts of 2-propanol is stirred for 3 hours at room temperature. The precipitated product is filtered off, washed with 2,2'-oxybispropane and dried, yielding 30 parts (73.4%) of 1,3-dihydro-1-(3-oxobutyl)-2H-benzimidazol-2-one.

후처리

  1. filtrationThe precipitated product is filtered off
  2. washwashed with 2,2'-oxybispropane
  3. customdried

출처 및 근거

ORD 기록
ord-2b18dee38ea94b61a1f9b789591ed763
출처 데이터셋
uspto-grants-1980_08
특허 번호
US04219559

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