(2-endo,3-exo)-Bicyclo(2.2.1)hept-5-ene-2,3-dicarbonyl dichloride → 5,6-Di(t-butoxycarbonyl)norbornene

HRID 1856610Notes

Reaction equation

HRID 1856610 reaction equation
[CH3:1][C:2]([CH3:5])([O-:4])[CH3:3].[K+].[CH:7]12[CH2:13][CH:10]([CH:11]=[CH:12]1)[CH:9]([C:14](Cl)=[O:15])[CH:8]2[C:17](Cl)=[O:18]>C1COCC1>[C:2]([O:4][C:17]([CH:8]1[CH:9]([C:14]([O:4][C:2]([CH3:5])([CH3:3])[CH3:1])=[O:15])[CH:10]2[CH2:13][CH:7]1[CH:12]=[CH:11]2)=[O:18])([CH3:5])([CH3:3])[CH3:1]

Participants

4

Reactant 2

HCID 98325(2-endo,3-exo)-Bicyclo(2.2.1)hept-5-ene-2,3-dicarbonyl dichlorideHCID 23665647Potassium tert-butoxide

Product 1

HCID 219223175,6-Di(t-butoxycarbonyl)norbornene

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

34 g (0.3 mol) of potassium t-butoxide was dissolved in 250 mL of THF in a round-bottom flask and then 22 g (0.1 mol) of 5-norbornene-2,3-dicarbonyl chloride was slowly added thereto at room temperature to be reacted at 45° C. for about 12 hours.

Workup

  1. customat room temperature to be reacted at 45° C. for about 12 hours

Sources & evidence

ORD record
ord-1dadfb5e83044056ba28095ee9da2ab1
Source dataset
uspto-grants-2000_11
Patent number
US06143466

Reaction notes

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