Bicyclo(2.2.1)hept-5-ene-2-carboxaldehyde → HCID 69823336, compound

HRID 1856612Notes

Reaction equation

HRID 1856612 reaction equation
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[Mg]Br.[CH:10]12[CH2:16][CH:13]([CH:14]=[CH:15]1)[CH2:12][CH:11]2[CH:17]=[O:18]>>[CH:1]12[CH2:7][CH:4]([CH:3]=[CH:2]1)[CH2:5][CH2:6]2.[CH:10]12[CH2:16][CH:13]([CH2:14][CH2:15]1)[CH2:12][CH:11]2[CH2:17][OH:18]

Participants

3

Reactant 2

HCID 95117Bicyclo(2.2.1)hept-5-ene-2-carboxaldehydeHCID 178419647HCID 178419647, compound

Product 1

HCID 69823336HCID 69823336, compound

Procedure

2-norbornyl magnesiumbromide (200 ml; 0.1 mol in THF) solution was poured into a round-bottom flask and 14 g of 5-norbornene-2-carboxaldehyde (0.11 mol) was slowly dropped thereinto and the reactant was reacted at 45° C. for about 20 hours.

Workup

  1. customthe reactant was reacted at 45° C. for about 20 hours

Sources & evidence

ORD record
ord-e142cc8d1db84d92a0b90afd806cede6
Source dataset
uspto-grants-2000_11
Patent number
US06143465

Reaction notes

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