HCID 20707075, compound → HCID 22132379, compound

HRID 1856650Notes

Reaction equation

HRID 1856650 reaction equation
C(OC(=O)[NH:10][CH2:11][CH:12]1[CH2:17][CH2:16][N:15]([CH:18]2[CH2:23][CH2:22][N:21]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=3[C:30]#[N:31])[CH2:20][CH2:19]2)[CH2:14][CH2:13]1)C1C=CC=CC=1>C(OCC)(=O)C.[Pd]>[NH2:10][CH2:11][CH:12]1[CH2:13][CH2:14][N:15]([CH:18]2[CH2:23][CH2:22][N:21]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=3[C:30]#[N:31])[CH2:20][CH2:19]2)[CH2:16][CH2:17]1

Participants

4

Reactant 1

HCID 20707075HCID 20707075, compound

Product 1

HCID 22132379HCID 22132379, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A suspension of 6 (100 mg, 0.232 mmol) and 10% Pd/C (30 mg) in 50 ml of ethyl acetate was hydrogenated at atmospheric pressure for 6 days. The suspension was subsequently filtered through celite and the solvent removed in vacuo to give the title compound.

Workup

  1. filtrationThe suspension was subsequently filtered through celite
  2. customthe solvent removed in vacuo

Sources & evidence

ORD record
ord-24a8fa96d0154e8281583a17a710255d
Source dataset
uspto-grants-2000_11
Patent number
US06143750

Reaction notes

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