化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → Tert-butyl azetidin-3-ylcarbamate acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | tert-Butyl (1-benzhydrylazetidin-3-yl)carbamate | HCID 13772848 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Tert-butyl azetidin-3-ylcarbamate acetate | HCID 21904480 | — |
反応手順
A suspension of 14 (4.6 g, 13.6 mmol) and 10% Pd/C (2.0 g) in 200 ml of 10:2:1 ethanol:water:acetic acid was hydrogenated at 50 psi for 24 hours. The suspension was subsequently filtered through celite and the solvents removed in vacuo to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06143750 |
| 出典データセット | uspto-grants-2000_11 |
| ORD ID | ord-a46d8f780040490b894d19a4de89a2cf |
| 出典メモ | uspto-grants-2000_11 |