HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1856748Generated: October 31, 2026
Sodium Azide → 6-(3-Azidopropoxy)carbostyril
https://huagongshe.com/reaction/1856748
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 6-(3-Chloropropoxy)carbostyril | HCID 14289480 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-(3-Azidopropoxy)carbostyril | HCID 22132605 | 97.3% |
Reaction Steps
A suspension of 6-(3-chloropropoxy)carbostyril (100 g) and sodium azide (33 g) in dimethylformamide is refluxed at 80° C. for 4 hours. After the mixture is allowed to cool, to the mixture is added ice-water, and the precipitated crystals are collected by filtration, washed with diethyl ether, and dried to give 6-(3-azidopropoxy)carbostyril (100 g) as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06143763 |
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| Source dataset | uspto-grants-2000_11 |
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| ORD ID | ord-2ca5e81abc2e4b138cef66f3ed51cc9c |
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| Source note | uspto-grants-2000_11 |
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