反应详情

温度

80 °C

A suspension of 6-(3-chloropropoxy)carbostyril (100 g) and sodium azide (33 g) in dimethylformamide is refluxed at 80° C. for 4 hours. After the mixture is allowed to cool, to the mixture is added ice-water, and the precipitated crystals are collected by filtration, washed with diethyl ether, and dried to give 6-(3-azidopropoxy)carbostyril (100 g) as a white powder.

1. temperatureto cool, to the mixture
2. filtrationthe precipitated crystals are collected by filtration
3. washwashed with diethyl ether
4. customdried