Phenylacetyl chloride → HCID 22132959, compound

HRID 1856819Notes

Reaction equation

[Br-].[OH:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-:11])=[O:10])=[CH:5][C:4]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[P+](C)(C1C=CC=CC=1)C1C=CC=CC=1.[C:32]1(CC(Cl)=O)[CH:37]=CC=C[CH:33]=1>>[C:15]1([CH2:16][C:17]2[O:2][C:3]3[CH:8]=[CH:7][C:6]([N+:9]([O-:11])=[O:10])=[CH:5][C:4]=3[CH:12]=2)[CH:14]=[CH:13][CH:37]=[CH:32][CH:33]=1

Participants

Reactant 2

HCID 7679Phenylacetyl chloride

HCID 86756007HCID 86756007, compound

Product 1

HCID 22132959HCID 22132959, compoundYield 58.5%

Procedure

40 g (81 mmol) of (2-hydroxy-5-nitrophenyl)-methyltriphenylphosphonium bromide and 21.4 g (162 mmol) of phenylacetyl chloride are treated under the conditions described in step 1 of Example 1. 12 g of product are obtained. Melting point: 100° C.

Sources & evidence

ORD record: ord-d3de58f062674e1d97d2df6543ff46c9
Source dataset: uspto-grants-2000_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06143772

Reaction notes

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