HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15380638, compound → HCID 15380639, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15380638 | HCID 15380638 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 15380639 | HCID 15380639 | — |
Reaction Steps
A solution of 4-{3-[(3-nitrobenzyl)carbamoyl]-5-ethylthiophen-2-ylcarbamoyl}cyclohexanecarboxylic acid in methanol is hydrogenated in the presence of Raney nickel. The catalyst is filtered off and the solution is concentrated. After recrystallization, 4-{3-[(3-aminobenzyl)carbamoyl]-5-ethylthiophen-2-ylcarbamoyl}cyclohexanecarboxylic acid is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143777 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-f1468b241cd64e888db57444a9accee6 |
| Source note | uspto-grants-2000_11 |