4-Phenoxypiperidine → Phenethylamine

HRID 1856859Notes

Reaction equation

HRID 1856859 reaction equation
[CH2:1](N(S(N1CCC(OC)CC1)(=O)=O)CC(OCC)=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O(C1CC[NH:36][CH2:35]C1)C1C=CC=CC=1>>[CH2:1]([CH2:35][NH2:36])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 188784-PhenoxypiperidineHCID 22615727Ethyl 2-[benzyl-(4-methoxypiperidine-1-sulfonyl)amino]acetate

Product 1

HCID 1001Phenethylamine

Procedure

ethyl 2-[benzyl-(4-methoxypiperidine-1-sulfonyl)amino]acetate (via methylation of the corresponding 4-hydroxypiperidine analog);

Sources & evidence

ORD record
ord-951a6c47361e4a2cb22d4cc685c5731d
Source dataset
uspto-grants-2000_11
Patent number
US06143744

Reaction notes

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