Hydrochloric Acid → HCID 54257333, compound

HRID 1856954Notes

Reaction equation

HRID 1856954 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][C:5]2[C:6](=[O:9])[CH2:7][O:8][C:4]=2[CH:3]=1.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][C:21]=1[O:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:17]=O.Cl>CO>[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:17]=[C:7]2[C:6](=[O:9])[C:5]3[CH:10]=[CH:11][C:2]([OH:1])=[CH:3][C:4]=3[O:8]2)[CH:19]=[CH:20][C:21]=1[O:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 2357176-Hydroxy-3-coumaranoneHCID 15633624-(Hexyloxy)-m-anisaldehyde

Product 1

HCID 54257333HCID 54257333, compoundYield 54.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

After 6-hydroxy-2H-benzofuran-3-one 1 g and 3-methoxy-4-hexyloxybenzaldehyde 1.88 g were dissolved in methanol 60 ml, concentrated hydrochloric acid 50 ml was added, and the mixture was refluxed for 2.5 hours. After the solution was cooled to room temperature, the precipitated crystals were filtered and dried over phosphorous pentoxide at a temperature of 60° C. for four hours under reduced pressure to obtain the desired compound 1.34 g.

Workup

  1. temperaturethe mixture was refluxed for 2.5 hours
  2. filtrationthe precipitated crystals were filtered
  3. dry with materialdried over phosphorous pentoxide at a temperature of 60° C. for four hours under reduced pressure

Sources & evidence

ORD record
ord-1a8901afbeba4dae8fa168b978f4195c
Source dataset
uspto-grants-2000_11
Patent number
US06143779

Reaction notes

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