HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-benzyloxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}-aminocarbonylmethyl]-benzoate → Ethyl 2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-2-buten-1-yl)-aminocarbonylmethyl]-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-benzyloxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}-aminocarbonylmethyl]-benzoate | HCID 21261753 | — |
| Reactant | 2-Allyloxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}-aminocarbonylmethyl]-benzoic acid | HCID 21261806 | — |
| Reactant | 2-Isopropoxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}-aminocarbonylmethyl]-benzoic acid | HCID 21261855 | — |
| Reactant | 2-Ethoxy-4-[N-{1-(5-methoxy-2-piperidino-phenyl)-1-butyl}-aminocarbonylmethyl]-benzoic acid | HCID 21261894 | — |
| Product | Ethyl 2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-2-buten-1-yl)-aminocarbonylmethyl]-benzoate | HCID 19025012 | — |
Reaction Steps
The mixing ratio of 75/25 is obtained from the corresponding ratio of intensities of the particularly characteristic signals in the 400 MHz-1H-NMR spectrum (CDCl3). The position of the signals is: 3-methyl-2-buten-1-yl compound: olefinic H: 5.25 (d), CH3 : 1.64 (s) and 1.77 (s), benzylic >CH-- 6.00 (t). benzylic CH2 --: 3.52 ppm (s) 3-methyl-1-butyl compound: CH3 : 0.90 (d). benzylic >CH-- 5.35 (m), benzylic --CH2 --: 3.54 ppm (s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143769 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-f69f334235c143dd90c3d80179498a30 |
| Source note | uspto-grants-2000_11 |