HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-Methyl-1-(2-piperidinophenyl)-1-butylamine, (S)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | N-acetyl-L-glutamic acid | HCID 70914 | — |
| Reactant | 3-Methyl-1-(2-piperidino-phenyl)-1-butylamine | HCID 10422052 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-Methyl-1-(2-piperidinophenyl)-1-butylamine, (S)- | HCID 10514609 | — |
Reaction Steps
Equimolar quantities of racemic 3-methyl-1-(2-piperidino-phenyl)-1-butylamine and of N-acetyl-L-glutamic acid were refluxed in aceton, whereby methanol was added in such an amount to yield a clear solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06143769 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-7821eeb086974856b385f4462f33d457 |
| Source note | uspto-grants-2000_11 |