HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1857099Generated: November 3, 2026
4-Chloro-6,7-dimethoxyquinoline → 6,7-Dimethoxy-4-(7-methoxy-2-naphthyloxy)quinoline
https://huagongshe.com/reaction/1857099
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chloro-6,7-dimethoxyquinoline | HCID 459610 | — |
| Reactant | 7-Methoxy-2-naphthol | HCID 853173 | — |
| Product | 6,7-Dimethoxy-4-(7-methoxy-2-naphthyloxy)quinoline | HCID 15479027 | 41% |
Reaction Steps
4-Chloro-6,7-dimethoxyquinoline (89 mg) and commercially available 7-methoxy-2-naphthol (209 mg) were mixed and stirred at 180° C. for 30 minutes, and the reaction mixture was then purified in the same manner as described in Example 2 to obtain 59 mg of the title compound (yield: 41%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06143764 |
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| Source dataset | uspto-grants-2000_11 |
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| ORD ID | ord-00d3728ce7a9451f89a38a67fd578b5f |
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| Source note | uspto-grants-2000_11 |
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