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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1857103Generated: November 1, 2026

6-Hydroxyquinoline → 6,7-Dimethoxy-4-(6-quinolyloxy)quinoline

https://huagongshe.com/reaction/1857103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-HydroxyquinolineHCID 11374—
Reactant4-Chloro-6,7-dimethoxyquinolineHCID 459610—
Product6,7-Dimethoxy-4-(6-quinolyloxy)quinolineHCID 2213262746.4%

Reaction Steps

Using 4-chloro-6,7-dimethoxyquinoline (90 mg) and commercially available 6-hydroxyquinoline (176 mg), reaction and purification were carried out in the same manner as described in Example 8 to obtain 62 mg of the title compound (yield: 46%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06143764
Source datasetuspto-grants-2000_11
ORD IDord-fef598185b944baaa1006a5356bc405e
Source noteuspto-grants-2000_11