Sodium ion → N-(4-Benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

HRID 185712Notes

Reaction equation

HRID 185712 reaction equation
[BH4-:8].[Cl:10][c:11]1[c:12]([OH:45])[c:13]([S:18](=[O:19])(=[O:20])[N:21]([CH2:22][c:23]2[cH:24][cH:25][c:26]([CH:29]([c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[OH:36])[cH:27][cH:28]2)[CH2:37][c:38]2[cH:39][cH:40][c:41]([F:44])[cH:42][cH:43]2)[cH:14][c:15]([Cl:17])[cH:16]1.[Cl:46][CH2:47][Cl:48].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[Na+:9]>>[Cl:10][c:11]1[c:12]([OH:45])[c:13]([S:18](=[O:19])(=[O:20])[N:21]([CH2:22][c:23]2[cH:24][cH:25][c:26]([CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:27][cH:28]2)[CH2:37][c:38]2[cH:39][cH:40][c:41]([F:44])[cH:42][cH:43]2)[cH:14][c:15]([Cl:17])[cH:16]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 28123BorohydrideHCID 585315993,5-Dichloro-N-(4-fluorobenzyl)-2-hydroxy-N-(4-(hydroxy(phenyl)methyl)benzyl)benzenesulfonamide

Product 1

HCID 58531518N-(4-Benzylbenzyl)-3,5-dichloro-N-(4-fluorobenzyl)-2-hydroxybenzenesulfonamide

Sources & evidence

ORD record
ord-8e3a040b35eb4201a72983dff50c0526
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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