4-Hydroxybenzophenone → HCID 22132702, compound

HRID 1857130Notes

Reaction equation

HRID 1857130 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[N:5]=[CH:4][CH:3]=1.[OH:16][C:17]1[CH:30]=[CH:29][C:20]([C:21]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[O:22])=[CH:19][CH:18]=1>>[CH3:13][O:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][C:8]=1[O:14][CH3:15])[N:5]=[CH:4][CH:3]=[C:2]2[O:16][C:17]1[CH:18]=[CH:19][C:20]([C:21]([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)=[O:22])=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 143474-HydroxybenzophenoneHCID 4596104-Chloro-6,7-dimethoxyquinoline

Product 1

HCID 22132702HCID 22132702, compoundYield 24.2%

Conditions

Temperature
180 °C

Procedure

4-Chloro-6,7-dimethoxyquinoline (91 mg) and commercially available 4-hydroxybenzophenone (243 mg) were mixed and stirred at 180° C. for 30 minutes. The reaction mixture was purified in the same manner as described in Example 31 to obtain 38 mg of the title compound (yield: 24%).

Workup

  1. customThe reaction mixture was purified in the same manner

Sources & evidence

ORD record
ord-b217d91975f24378adc435ab13226739
Source dataset
uspto-grants-2000_11
Patent number
US06143764

Reaction notes

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